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Sunday sees the initial Wear-Tyne derby after 2024, but which side will celebrate – Sunderland or the Magpies?
"During the bulk of last season, you couldn't have imagined Sunderland earning promotion and holding their own with Eddie Howe's Newcastle, never mind being above them in the table," remarked pundit Chris Sutton.
"It is very different now, and the way they play makes me think they've got a real chance."
Sutton is making scoreline guesses for all 380 Premier League games this season, against artificial intelligence, fans and a variety of guests.
For this weekend's fixtures, he faces off against England Gaming star Daniel 'Stingray' Ray.
Ray is vying for victory for the eLions – the Football Association's recognised esports team – at the gaming title Uefa eEuro 2025 finals tournament, which is being held at Twickenham Stadium on Saturday.
You can watch Uefa's video platform, IG Live and short-form video channels, as well as EA Sports FC Twitch and YouTube and England's Twitch.
What are your thoughts with their forecasts? You can make your own projections below.
The most commonly selected scoreline selected for each game is featured in the scoreboards at the end of this page.
A correct result (selecting a win, draw or defeat) is worth 10 points. A perfect prediction earns 40 points.
Ray, who represents his club side and Manchester City as well as England, is entering the fray at the eEuros finals after getting through the qualification rounds.
Eight players will represent their nations at the finals in a straight knockout, vying for a $100,000 prize pool and a highly sought-after spot in the global championship qualifiers, with Denmark's Anders Vejrgang defending the title he won last year.
"My mindset is really good for it," Ray said. "There's a really good coach with me and training has been going well.
"It's always an honour to play for your country. Naturally when you are younger, you imagine doing it as an professional footballer, but when you pursue a career in this job and there is an opportunity to represent England, putting the shirt on is something special.
"I overcame Vejrgang 9-4 in qualifying to get here. I've played against him throughout the year just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"In my opinion he is the top competitor in the world so defeating him in a tournament like this just gives you a crazy boost of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The Blues were outstanding against the Gunners at the end of November, when they got a draw after being reduced to 10 men, and I was thinking they've turned a corner, they could possibly be challengers for the crown.
However, since that game, however, they were outfought by Leeds, looked lethargic against Bournemouth and this week got turned over by Atalanta in the Champions League.
So manager Enzo Maresca is in need of a win here to return to winning ways, but it is a tough ask because the Merseyside club are such a threatening team.
Two of their stars are playing really well and Everton have got a bit of momentum at the moment.
Based on recent performances you would likely back the visitors, while the most sensible prediction would likely be a draw, but I'm throwing caution to the wind.
The Blues have failed to given me any compelling evidence to back them recently, but I just have a feeling Chelsea will win this match because they are at home and they are in need of three points.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be interesting to see what we get from the Reds.
It was great to see for Reds boss Arne Slot to get such a crucial result at Inter Milan on Tuesday following all the controversy with Mohamed Salah this week.
Slot ought not to put up with that nonsense. I know Salah has been a great for the club but fundamentally Slot just wants to win games and there is no bias in his team selection.
Liverpool changed their shape against Inter and went with a midfield diamond formation and two up top.
All the talk is going to be talking about whether Salah is back for this game, but the only way he is going to be reintegrated is if he says sorry.
Slot's attention will be on winning this game, but it is a challenging encounter.
One might suggest it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are vulnerable at the back too.
Liverpool need to get back to a consistent run of form, but I am not sure how much their efforts at the San Siro will have affected their stamina.
I have whacked a couple of Brighton players in my Fantasy Premier League side, so they will likely do poorly - but I do think they can get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Wearside club have had the week off while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
With the exception of their superb performance against Everton a couple of weeks ago, Newcastle's away form hasn't been great, particularly straight after they've played in the Champions League.
It is anticipated that that trend to continue on Sunday, and their fatigue is likely to be a significant issue in how this game goes because of their rivals' high press.
It was evident how unwavering Regis le Bris's side are. They overpowered the Gunners, and it was incredible to watch.
Commentators talks about how Granit Xhaka has been outstanding for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays in midfield with him, has also been one of the top transfers and deserves some attention too.
All signs point to this being the best game|most exciting fixture